PRP Studies and Research Summary
In the last 4 years PRP has grown from relative obscurity to acceptance by mainstream medicine with over 7000 published articles and an annual growth rate of 200%. In this article/video we look at the clinical research data published on the efficacy of PRP.
Filardo did a long term follow up study of PRP treatment for osteoarthritis of the knee. It demonstrated that the majority of patients had significant pain relief for one year, with almost no decline during this time. This is very similar to the Surecell data collected by Dr Peter Lewis. Between one year and two years there was a reduction in pain relief. But even after two years, pain was halfway between maximum relief and baseline.
Gosens studied 100 patients randomly allocated to PRP or cortisone injections for tennis elbow. The group treated with cortisone had the quickest initial improvement, but by 9 weeks the PRP group not only caught up but went on to better results while the cortisone group returned to baseline after 6 months.
Cerza compared the results of ACP (PRP) vs hyaluronic acid injected into osteoarthritic knees. At baseline before treatment the PRP group of patients had a little more pain than the hyaluronic acid group. After 4 weeks the PRP group had improved more than the HA group. At 12 weeks and 24 weeks the gap between the two groups increased because the HA group deteriorated while the PRP group was continuing to improve even though they were not getting any more treatment.
Surecell data confirms continuing improvement after treatment which suggests that the action of PRP is more than just a “lubricant” or anti-inflammatory. PRP causes long term healing due to growth factors.
Cerza also looked at his results according to severity of initial osteoarthritis. This graph shows a similar improvement in pain score across three grades of severity, which suggests that even patients with the most severe OA will likely benefit from PRP.
The last years have seen numerous studies and publications which show that patients feel better after PRP treatment and MRI scans confirm substantial physical improvements.